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2.1 Corticosteroids In development, metabolism, and immunity, adrenal steroid hormones (known as glucocorticoids) can have an important impact, and corticosteroids (CS), which are synthetic analogs of glucocorticoids, have anti-inflammatory and immunosuppressive effects ( In vivo , CS inhibits the maturation, differentiation, and proliferation of virtually all immune cells and reduces the inflammatory response by inducing vasoconstriction and reducing blood flow to the lesion ( EOLP has been successfully treated with clobetasol patches (Rivelin-CLO) in clinical trials recently